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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7b455d9a76974860d4487ba0898d5d251575eb4f79073da12961b606c33ceb0' 
  AND token = 'ZarPQ0gaPnfgPXdgEC3MySho8X6C29qiiPZ1OZtAeWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}