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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adfe02c13d9db5d312f49ac8843ac94533f4617d23485df186fc322b3b2791a5' 
  AND token = 'iSLAlk4TW2Pl88u1ENWmBWh6WwKyl7+HA4BXu3LCY0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}