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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b408e8fdba1477df7e4ba408a660de6f0ef73a37628df73694159eabe0f5e500' 
  AND token = 'uhwOTceWkCshG5vXVDmYmzjbegFuTF2jQs9XAJkjdbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}