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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e7a75a64eff5d26ef577ed2f09dea5e1f511ad89d96414a44688909f6740c25' 
  AND token = 'lvxq2BuwSzZ5F1edNUaCv2gUZj7GXcYMlDqt1nuqPCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}