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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6337d880012cb6f3e3c64cd4bfbc4229d13e858b4e9806db564f5e6bd7c50672' 
  AND token = '6dpjipp5R9xCGKwL6rpgcHrEb+1dvjZI+sKZaxl5CVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}