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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '337710b73062c2818e1822b1afa64cfcb51dd1f16f6736bc2fef50eab4807ecc' 
  AND token = 'zyOTbfpkLVOy6JAM7BJRpLer/tH81wgiudaWT2Y7Urg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}