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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0001baa55eeeb00cf733d09a714c3f305f2dc81dfab687e26c65c3da62fcb044' 
  AND token = 'UqG9Makm3hBu9Z7PbfHJeFrwwFEPVRGMjLEtjKh45IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}