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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4da271563d5a379f4afa2a5eba7cef4eada1b5c7776963cc75e5c1f5b2aba00' 
  AND token = 'QyqFu3MODD5xmyfhb8up1a0+b+lB159Dk5yzJa+Snmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}