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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '565f6ac32b559395ba136fbbcbc5b81fb935d323b5a5ca46d44375d6486af6a4' 
  AND token = 'oTY/9er/cSHYCcwUm+JaYsPMB0XR970pI2NeSrYs6uE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}