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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81a5c5eb6f8e6efe447367b336b6571676f5f08050c9aa2a08fc8a78f184d7b6' 
  AND token = '2e7S3n5WaSOF27lqSgIG9ixMpnJjdbGpuChk0liZkzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}