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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eeb2db597a491ab5d475d30856c947589d7833d0f18b2d4c3878d4343ee24ce' 
  AND token = 'ZWT2GxBpmTwckf6cpMpXXl4dAnPS4YAiRWue2MMT3dM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}