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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55e1954e52e506a20159a8482e7f8d31e64f8b9efc7dafe41d5b7d7a6df921de' 
  AND token = 'laOoHiz48rx7l5vxOmxs2sRVTCwMMPRI1i9ORlN7WUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}