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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c41ffb92f7b2bf432a87b2ea0d5f80e339e7b70cd74329e94d7ff29527a3715' 
  AND token = 'O2ExemC8WXmNVTsfX6Ivkb4Ez/2xQ6LMUKrLdyuwl3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}