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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2f3c1053e8141fa816be52285fb162803841ca2eac0d8e4e412752df9fc6815' 
  AND token = 'w4t4qhpSOWz4tBQ249/fFanIGXoUj0wGYaHJoSj9Dpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}