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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dd8005028d3312f533f24b1b1359ca9d77e21d0bd21401e5f8eb4e6d4567482' 
  AND token = '/yVox8BlYn+efeDLNjd20tCZx3G+4iiXGb4UWOCAf3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}