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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2752bb12a18aca1093573c3797fce19fa3247e088ca4b82a646c1484e2c857c1' 
  AND token = 'PGolXrOstGRafyw1hiM3UrtolWnorh+T7ZT8obm6xwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}