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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4f49b547b0ecf0b05ff04e2610d62193e0a50683d55f71ea405bd62b4b79980' 
  AND token = 'ZKMQB1V0MWQTak1HL0siFus/QGwecsVJQLLXz48UHe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}