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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6417e6df7ff6f5ad1a4d25d44081e502d79ce7afd18c7d8fb413dbda4a627f5a' 
  AND token = 'HOLet8shCuFCnOIGRDTok1/AIs3PRKkP/PIiifWnh1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}