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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b41159b4263a5616bde42a23bbb07bf3389526ed5a769e22bc7b19d3a105f38' 
  AND token = 'i8vYfTuQMl7mbGtuL1KUVSNWDQTNKQWDwqDuDH8NxNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}