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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28e1c949627602e2956b25406ed157eb2b924538c493ff2b9641750bc2a69827' 
  AND token = 'kg1u5mzWD0zsCDlXdFJc14sIj++cXQwhdkrCQb6rVDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}