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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d0efc1e5c7c55e219d1a0434e69725ac82fa1a586f411e0d6c5e80d972da4a5' 
  AND token = 'aBr33DNBKCTZUkNa8zSBzOCay1Dqd7ENKPF0jJnb91o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}