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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4e63f60fb6c7012428da824fb6fdab97c9f338ad8663dcc71bcd763f15ca488' 
  AND token = 'TtWZVuOSs5MLHMbL/V1JfAcKoau5qUe7br99UZS5Gfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}