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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b7ebfb8a9d528e51f57993f947bbbf9d9d2760b8b71f62e7f9301ee5b8c1c45' 
  AND token = '0A9ASxZxoLttVWuGMqcnPkHvwMOfFaz3+BHAwkYtaK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}