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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccb6cd169c090c38548f8a23e19644a83341f7ff83f8c561171e2a9e25b28d5a' 
  AND token = 'qNPSpeiMtb0SFGiy+nelUs4mPyqYocMIEBEdjMVp06w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}