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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0458946f2059a93ada3f16bc67ae7a77a65db4a1e58bd69865981c3b024b1d59' 
  AND token = 'Q8P7PuFp4pKLgcdfb1XDkmDFCtGm8frqHDaoYiypcaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}