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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e529447b8f3dd90d46d0140c8eb1d62d268a5cfed9a8d471eb24488afa42540' 
  AND token = 'AvofwXIEQYuzVTrW/c2T6t0QFU157BLm7DZXTAegTlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}