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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d21fe1a0917c6b178d0deab63f688eb2e168957c57b09a6dd5cb6e3c95e9a12' 
  AND token = 'LyMf/B+sjHASs408SIsWD/PesJ4L8R460LTLA138VS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}