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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38c1601f3c7abd0a8f74beee7c521ed65e4b181c657b8336f655f72d4870fec2' 
  AND token = 'rHUCDC8DYTTvj9IOVlXQ6mvd9Fjld7glLUoTM8grZFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}