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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '466b184a2d99b8ce4f9e9e218315b764d5c353b68d1b55ebd916f64d2e41845b' 
  AND token = '3754kkqp8OsFO/AF+TphwSqmLPymyPwjPkUVS0R74MA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}