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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '249bb71c8bc2d8c45126b384b60ecf17b85771b1f48900b98b9ece0c44b0f54c' 
  AND token = 'sDiiSgIxqhhGcSZusoZplTw1PkOhZctvGa1h2mMiRyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}