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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf67afc0f55e600fd58d733805116a6d9438214c3f033c6d692a840f7e0cc1b1' 
  AND token = 'W8e9BfY+H7VGXzonfAoZ9JjIqRVYlRyX4Mis+T3mEEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}