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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c7cef038541e4ffcb8ed1b6f1915d84f46627631be57bb891a02f20257050df' 
  AND token = 'VO7sIXg6ejKYCRxPkMS7fJd8RWW0vV2ynUILxP5/fgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}