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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800dc653da43e4bcb510b1f11d9bf3fa5de7078497a7e8709a917108c0734eb1' 
  AND token = 'g25JTRmjy+LYkq1RU87vJUyRFWqssnCHrNi/oDzHe4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}