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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d753da50c0cff927581ac1a705c8c2110776dd5c4101fb17d650d39b27e999b' 
  AND token = 'IipuWneyJ67uCfFZGrT0E9lde4qm4TQQIEX9sGsWkL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}