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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8ed61118fda81e98463365b3f725fbc93467db8a1800ceb447cc5e8c39a7f3b' 
  AND token = 'GQxTZNjUJM2SQgDEkv6vgvlrKaBoNE5ZuepMrmBl6Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}