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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c1d16c84d6e9d40697b5bf595df17b11e027c6fa50da32403107771d37aa5b5' 
  AND token = 'j6Mt8HiMRdq34AbYCtL7gazoC88qzldgEiMBCD70UZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}