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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cbb30b07e6c7e3c6322fb3a1cfbb3acacf51f492622b397d45fef050332126d' 
  AND token = 'ezDdt+15vWQQ+iS7Us4b4aRAd3XRgVOzAjrs/7wN0fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}