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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '753ca517ce5b8056b9c4c8b713175fc24402f975158545af0dbc9051f176b631' 
  AND token = 'jty1Lh8xSzeI5YoVQ/HUcDFVWAsLMHdcZl2TSkgxKUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}