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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b01ab170d8ae57c5c616ad66935ee972218035cee5550be5bf639c43e65d2d4' 
  AND token = 'ieuItszJYYs7OnoCxsiVUo58LsYDqmR30H/GZ5mgHuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}