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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad122c83defc531252f73f5b3dd7f1d5ed00d66b5d1a3603752c3ef3175dae0c' 
  AND token = 'JcV51lPzQ0GSY4mI4eJoLq+u4n1I3/uRbPO4oGwTGXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}