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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18e1c0800be9a4a0f04d3d096137604d7241222fd776c1fb71a1e68d84080612' 
  AND token = '6KkeKDXXCEMq0wN5CvS0idG2OW+YTpGpe+sBXdcRmn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}