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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e95a4895589701364b26f9d0e76fa3856b1835f342de5b2318215dc5dee5b8e' 
  AND token = 'V96TUUg4k0ZyE0eO0XnMonwST8PjpZUiVhpNINYPB9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}