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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a17d28e98dacff736dbc3b1494bda3db8a0d80ddbdb6f7485f19438972de3ea' 
  AND token = '2wr4Dt4fVY1LX5/8Ya4+ahVKNegdwJpMYsnqKf4bUPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}