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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e22fb1081120126c604a87a055994f422e15477f7ff7d117a4a9292ab358c68' 
  AND token = 'H07iP74hOPSEJ+dxIO5l3gen1o/RYYsY9AkUQiCw1gc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}