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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29cbe89dba3b3aebef3dc838d76c3d0e45b9c37ab74fb8975f649f02d58b4e5d' 
  AND token = 'rtnVB/1R+1n0YP3FE2Rha0Pf0TOevTBzfST/5C+joD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}