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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af450c744db6f36b7a11641bf02431c4ee20b3b4fd17abe624e6d036d1ef9854' 
  AND token = 'CtFUGiBM5nvLMMOyE667KqXdixLgAeDdsgN2IEbzVUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}