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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5f9cfad7b6acf0cc1b3d539b821fe39cffdf6c63ca4cc0f96400a035782a321' 
  AND token = 'hPL5Gh4V4ZUap9Ju31wQm+12qDikBhCiP2vFtgMQfTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}