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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '306e5023a7c0160e818fcf59db9637cb5941c81fa6a2fd5cd60ce332446c7825' 
  AND token = 'qAvCdPjRL2pquqkkS+nw3ME7pB9kY12Gwr2bY1urcco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}