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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '754b0d74f3a75dee097f358b551bf916366cc9500007f7c47f2c0f3d0cf62c40' 
  AND token = 'bYyNf940WaUYtxSoprEn7nzJTC/qDlvpprrKXj8fuaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}