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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2d707b3afe607b6c0cb569b1ce306dae9ee94b3d95579aa551e57c4bad83aac' 
  AND token = 'Oagg+hS7L4/emz709kiZtqwGSIX3oPhSYVNAfnXuRk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}